Molecular detection of Borrelia burgdorferi sensu lato in questing ticks: One year of sampling in Bologna (Northern Italy).
Borrelia burgdorferi sensu lato (s.l.) includes several genospecies responsible for Lyme borreliosis (LB), a major zoonotic disease transmitted by Ixodes spp. ticks. In Western Europe, LB incidence has risen in recent decades, with documented expansion into previously non-endemic regions. A cross-se…
Stepwise management of median arcuate ligament syndrome with visceral artery aneurysm: Surgical ligament release followed by percutaneous transluminal angioplasty.
A woman in her 20s presented with an 8-year history of postprandial abdominal pain. Contrast-enhanced computed tomography revealed severe stenosis at the origin of the celiac artery, collateral circulation from the superior mesenteric artery, and an associated inferior pancreaticoduodenal artery ane…
Inhibition of Janus kinase/signal transducer and activator of transcription reduces nociceptive sensitization in a murine model of complex regional pain syndrome.
Complex regional pain syndrome (CRPS) is a disabling condition relying in part on the production of pain-supporting autoantibodies. The Janus kinase/signal transducer and activator of transcription (JAK-STAT) signaling system regulates the adaptive system of immunity and is targeted to control autoi…
Embolization of spontaneous retroperitoneal bleeding fed by aneurysmal arc of Bühler: Case report and technical considerations.
The arc of Bühler (AOB) is a rare embryonic anastomosis between the celiac artery and the superior mesenteric artery, which may become a crucial collateral pathway in cases of celiac axis stenosis. We report a challenging case of a 70-year-old woman presenting with hemorrhagic shock owing to a…
Dirofilaria immitis heartworm infections in Hungarian zoo animals.
Dirofilaria immitis is a worldwide spread, mosquito-borne nematode of zoonotic concern, with domestic and wild canids serving as the main reservoirs of the infection in Europe. In this study we describe eleven cases of cardiovascular dirofilariosis in Hungarian zoos, including three Eurasian wolves…
Perioperative pregabalin does not alter behavioural or diffuse noxious inhibitory control responses in 2 rat models of chronic pain.
Multiple mechanisms contribute to the experience of pain where the use of model organisms to dissect mechanistically sensory regulatory circuitry is a vital component of discovering underlying causes of persistent pain in disease states. Such disease states can be modelled in animals using surgical…
Evaluation of a modified next-generation sequencing assay to detect Borrelia, Anaplasma, and Babesia in blood and ear tissue samples from field-collected rodents.
Efforts to monitor the expanding geographic distribution of pathogens associated with Ixodes scapularis Say (Acari: Ixodidae), and to evaluate the outcomes of environmental control interventions aiming to reduce the intensity of enzootic transmission of these pathogens, are dependent on sensitive an…
Protective Effect of Uric Acid on Rat Model of Irritable Bowel Syndrome Requires Brain-Gut Communication Through Vagal Cholinergic Pathways.
Uric acid (UA) is an endogenous antioxidant that protects against neuroinflammatory diseases. Although irritable bowel syndrome (IBS) is considered a disorder of gut-brain interaction, the role of UA in IBS remains unclear. An experimental rat model of IBS was induced using laser-induced shock waves…