Effects of caffeine gum on same-day and subsequent neuromuscular performance under a standardized resistance-priming condition in male basketball players.
This study examined whether 3 mg·kg-1 (CAF3) and 6 mg·kg-1 (CAF6) caffeine gum, administered before a standardized resistance-priming (RP) protocol, produced additional neuromuscular performance advantages over placebo (PLA) at 1 h, 24 h, and 48 h in male basketball pl…
WIPButyrate produced by the Lycium ruthenicum polysaccharide alleviated sleep deprivation-induced chronic fatigue syndrome in mice through promoting microglial autophagy.
This study explored whether Lycium ruthenicum polysaccharide (LRP) influences gut microbiota-derived short-chain fatty acids (SCFAs) and neuroinflammatory responses in a sleep deprivation-induced CFS-like mouse model. Oral LRP was associated with improved fatigue-related behavioral performance, redu…
Circulating Antinephrin Antibodies in Adult Chinese Patients With IgAN and Nephrotic-Range Proteinuria.
Antinephrin autoantibodies are detectable in podocytopathies such as minimal change disease (MCD) and primary focal segmental glomerulosclerosis (FSGS); however, their prevalence and clinical relevance in IgA nephropathy (IgAN) with nephrotic-range proteinuria (NRP) and nephrotic syndrome (NS) are u…
Evaluation of serum human galectin 3 as a marker of activity in inflammatory bowel disease in comparison to fecal calprotectin.
Inflammatory Bowel Disease (IBD) is a chronic and recurring inflammatory condition of the gastrointestinal system that has an unknown cause and is marked by periods of relapse and remission. Endoscopy remains the gold standard for assessing disease activity; however, noninvasive biomarkers are neede…
Microvascular barrier - Transdermal and topical drug delivery in Raynaud's Phenomenon.
Raynaud Phenomenon (RP) is a peripheral vascular disease that results in episodes of vasospasm of the microcirculation of hands and feet, which causes ischemia, pain and functional deficiency. Traditional systemic treatments of RP, such as calcium channel blockers and phosphodiesterase type-5 inhibi…
Long-term treatment with Eptinezumab in special treatment situations: Real world data.
The neurotransmitter Calcitonin Gene related Peptide (CGRP) is one of the key players driving migraine attacks. Randomized placebo-controlled studies with eptinezumab, a humanized monoclonal IgG1 antibody directed against CGRP, provided evidence for its migraine prophylactic effects. This study show…
A New Infrared Thermography Based Approach to Ankylosing Spondylitis Assessment: A Preliminary Study.
The clinical assessment of ankylosing spondylitis (AS) traditionally relies on hospital-based procedures, imposing a significant time and economic burden on patients. To address this challenge, this study proposes a non-contact, home-based method for assessing AS status by analyzing infrared thermal…
Serum Sirtuin 1 as a potential indicator of disease activity and severity in systemic lupus erythematosus patients.
The aetiology and pathophysiology of systemic lupus erythematosus (SLE), are yet unclear. Autoantibodies that target various organs and tissues are produced as a result of SLE patients' poor immunological tolerance. Sirtuin-1 (SIRT1) is a histone deacetylase that has a major role in immune responses…