Compression of nerves or blood vessels between the collarbone and first rib, causing arm pain and numbness.
✦ AI summary
Thoracic Outlet Syndrome (TOS) refers to a group of conditions caused by compression of nerves or blood vessels at the base of the neck/shoulder area, and it includes three main types: neurogenic (nerve-related), venous, and arterial [3]. Arterial TOS is described as rare (less than 1% of cases) but can cause serious problems like reduced blood flow, clotting, and tissue damage; one case report describes a woman whose arterial TOS was linked to an extra cervical rib and was treated surgically, with imaging later showing nerve-related swelling in shoulder muscles afterward [1]. A preliminary study looking at people who had surgery for neurogenic TOS found a notably higher-than-expected rate of birth-related trauma (like shoulder dystocia or forceps delivery) in their history, raising the possibility that early-life injury may play a role in later TOS development, though the researchers describe this as a small pilot finding needing further study [3]. For diagnosing neurogenic TOS, one study looked at ultrasound-guided injections into different muscles/nerves near the thoracic outlet to see which reproduced relief of symptoms; it found that injections into the pectoralis minor muscle were as
This is an AI-generated summary of the sources below — not medical advice. Always talk to a doctor or pharmacist about your own situation.
Arm painNumbness in fingersWeaknessCold handsNeck painShoulder pain
From compression to denervation: Multimodality imaging of cervical rib-related arterial thoracic outlet syndrome.
Thoracic outlet syndrome (TOS) encompasses a spectrum of disorders caused by compression of neurovascular structures at the thoracic outlet. Arterial thoracic outlet syndrome (aTOS) is rare, accounting for less than 1% of cases, yet carries significant morbidity due to arterial injury, thrombosis, a…
Surgical outcomes following spinal fusion for cervical versus noncervical fractures in ankylosing spondylitis and DISH.
Ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH) are 2 distinct spondyloarthropathies characterized by progressive spinal ankylosis. Despite their differing pathophysiologies, both conditions create long rigid spinal segments that are vulnerable to unstable fractures.…
Birth Trauma and Thoracic Outlet Syndrome: Preliminary Evidence.
Thoracic outlet syndrome (TOS) arises from compression of neurovascular structures as they traverse the thoracic outlet at the base of the neck, with 3 main types: neurogenic, venous, and arterial. Established risk factors include acute trauma, repetitive upper extremity use, or congenital anatomica…
Tethered Cord Syndrome and Spinal Epidural Lipomatosis in a Child With RALA -Associated Hiatt-Neu-Cooper Syndrome.
Pathogenic variants in RALA cause Hiatt-Neu-Cooper syndrome, a rare and clinically complex neurodevelopmental condition characterized by developmental delay, hypotonia, and intellectual disability, with distinctive craniofacial features. The disease is also associated with variably occurring seizure…
Ultrasensitive Immunoassay Using a Novel Galactose-Deficient IgA1 Antibody and Its Clinical Application in the Diagnosis of IgAN.
IgA nephropathy (IgAN) diagnosis remains dependent on invasive renal biopsy because currently available serologic biomarkers, including galactose-deficient IgA1 (Gd-IgA1), have limited diagnostic performance. This study aimed to develop and evaluate a high-sensitivity time-resolved fluorescence immu…
OGN inhibits apoptosis and ferroptosis via FSHR in human granulosa cells: implications for polycystic ovary syndrome.
Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by granulosa cell dysfunction, including impaired proliferation, excessive apoptosis, and ferroptosis, which contribute to abnormal follicular development and ovarian dysfunction. This study aims to investigate…
Stimulating Thyrotropin Receptor Antibodies Enhance the Expression of Both Thyrotropin Receptors and Insulin-Like Growth Factor 1 Receptors in Fibroblasts.
Thyrotropin (TSH) and insulin-like growth factor 1 (IGF-1) signals have been shown to be additive in their action on thyroid cells and fibroblasts, and this coordination emphasizes the role of TSH receptor (TSHR) and IGF-1 receptor (IGF-1R) signaling exerted by stimulating TSHR antibodies in patient…
Mild Thyroid Eye Disease-The Most Common yet the Least Studied Presentation of Thyroid Eye Disease.
Mild thyroid eye disease (TED) is the most common form of TED, yet it is the least studied. Uncertainties about the natural history and prevention, and underfunding for clinical research, are an obstacle to improving the management of this important group of patients. The available evidence suggests…